Bullous Pemphigoid with Localized Umbilical Involvement

Bullous pemphigoid with localized umbilical involvement.

© 2009 The Authors. doi: 10.2340/00015555-0644 Journal Compilation © 2009 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Bullous pemphigoid (BP) is the most frequent autoimmune bullous disorder. BP is associated with anti bodies to two hemidesmosomal proteins, BP180 (type XVII collagen) and BP230 (1). The disorder usually affects elderly people, and severe pruritus is typically present. In the...

Localized genital bullous pemphigoid; A case report

Bullous pemphigoid (BP) is an autoimmune bullous disorder with urticarial pruritic papules and plaques and tense bullae in flexural surfaces of body. The localized form of the disease is a rare variant which can be triggered by different stimuli. Hereunder, we report a patient with the local type involving genitalia without any triggering factors.

Laryngeal involvement in a patient with bullous pemphigoid.

Bullous pemphigoid

Bullous pemphigoid

Disease summary: Bullous Pemphigoid is an acquired, chronic, blistering autoimmune subepidermal bullous disease in which autoantibodies are directed against component of basement membrane zone of the skin [1]. It is characterized by formation of cutaneous bullae on the skin and mucous membrane. The pathogenesis involves migration of inflammatory cells into subepithilial tissues due to activatio...